Altered ANG/TIE gene expression in advanced ovarian cancer is not accompanied by disproportionate body water accumulation relative to perioperative fluid balance
Sarah Reifenhaeuser, Katrin Stein, Stilla Frede, Eva K Egger, Alexander Mustea, Mark Coburn, Sven Klaschik, Martin Soehle, Tobias Hilbert · 2026
Read Altered ANG/TIE gene expression in advanced ovarian cancer is not accompanied by disproportionate body water accumulation relative to perioperative fluid balance by Sarah Reifenhaeuser, Katrin Stein, Stilla Frede, Eva K Egger, Alexander Mustea, Mark Coburn, Sven Klaschik, Martin Soehle, Tobias Hilbert (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13534688.txt.
Description
Sarah Reifenhaeuser and eight co-authors report a 2026 study of women having major surgery for advanced ovarian cancer. Such surgery needs large amounts of fluid to keep blood pressure steady. Gene shifts in the blood vessel system had raised a doubt: do these patients leak fluid in a way that drives the demand?
The team checked gene activity in muscle tissue and measured body water before and after surgery in twenty patients and sixteen controls. Patients did end surgery with a larger fluid balance per hour and needed more of a pressure-raising drug, yet the rate of fluid given during surgery matched the controls. Body water measures did not show extra pooling beyond that balance, so the gene shifts alone do not prove a leak-prone state.
Catalog record
| CREATOR | Sarah Reifenhaeuser, Katrin Stein, Stilla Frede, Eva K Egger, Alexander Mustea, Mark Coburn, Sven Klaschik, Martin Soehle, Tobias Hilbert |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |