The plasma protein profile of left ventricular diastolic function

Elias Eerola, Lars Lind, Andrei Malinovschi · 2026

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Description

Elias Eerola, Lars Lind, and Andrei Malinovschi hunt for blood proteins tied to how the heart relaxes in a 2026 study. The left ventricle's filling phase, called diastole, stiffens with age and disease, and that stiffness is an early step toward heart failure. Blood proteins might flag the change before symptoms start.

The team drew on two Swedish population studies, one of seventy-year-olds and one of fifty-year-olds. In the older group they tested a panel of eighty-six heart-related proteins against ultrasound measures of filling. Hits were then checked in the younger group, and a far larger protein panel was screened there too. Seven proteins kept a replicated link to a key filling ratio. The profile gives researchers fresh leads on the biology of a stiffening heart.

Catalog record

CREATORElias Eerola, Lars Lind, Andrei Malinovschi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE51 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13534439

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