Long Non-coding RNA TLX1NB Regulates Inflammatory Response in Periodontitis by Interacting With Matrix Metalloproteinase 8
Shouxiang Yang, Wanting Yuan, Ziqiong Yang, Jiaxuan He, Xiaoqian Wang, Lei Lu, Zhijia Xu, Xiaoyu Yao, Chunai Zhan, Long Mei, Wanyu Zhang, Wei Shao, Xiaoyu Sun · 2026
Read Long Non-coding RNA TLX1NB Regulates Inflammatory Response in Periodontitis by Interacting With Matrix Metalloproteinase 8 by Shouxiang Yang, Wanting Yuan, Ziqiong Yang, Jiaxuan He, Xiaoqian Wang, Lei Lu, Zhijia Xu, Xiaoyu Yao, Chunai Zhan, Long Mei, Wanyu Zhang, Wei Shao, Xiaoyu Sun (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13534188.txt.
Description
Shouxiang Yang and colleagues study in 2026 a long non-coding RNA named TLX1NB in periodontitis, a long-term gum disease driven by bacterial films. Gene scans found TLX1NB raised in gum tissue from patients, and a lab model with stimulated gum cells showed the same rise. The RNA sits mostly in the cell nucleus.
Lowering TLX1NB cut key swelling signals, eased cell death, and boosted cell growth in the model. Tests showed TLX1NB binds MMP8, an enzyme that breaks down collagen, and both act together on swelling paths. Readers see a fresh target for calming gum tissue harm.
Catalog record
| CREATOR | Shouxiang Yang, Wanting Yuan, Ziqiong Yang, Jiaxuan He, Xiaoqian Wang, Lei Lu, Zhijia Xu, Xiaoyu Yao, Chunai Zhan, Long Mei, Wanyu Zhang, Wei Shao, Xiaoyu Sun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55579 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |