Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure
Tian Xie, Alireza Ani, Ahmad Vaez, Ilja M Nolte, Shaoyong Su, Mami Ishikuro, Siqi Wang, Wenbo Zhang, Ana Goncalves Soares, Ehsan Motazedi, Lucinda Calas, Justiina Ronkainen, Casper-Emil T Pedersen, Xueling Lu, Sara E Stinson, Janine F Felix, Evelina Stankevic, Carol A Wang, Elisabeth Thiering, Dietm · 2026
Read Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure by Tian Xie, Alireza Ani, Ahmad Vaez, Ilja M Nolte, Shaoyong Su, Mami Ishikuro, Siqi Wang, Wenbo Zhang, Ana Goncalves Soares, Ehsan Motazedi, Lucinda Calas, Justiina Ronkainen, Casper-Emil T Pedersen, Xueling Lu, Sara E Stinson, Janine F Felix, Evelina Stankevic, Carol A Wang, Elisabeth Thiering, Dietm (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13533560.txt.
Description
Blood pressure in childhood casts a long shadow, but the genes behind it have mostly been mapped in adults. Tian Xie and a large international consortium run the biggest gene scans yet for children's blood pressure and heart rate. They pool data on more than twenty-eight thousand children of European ancestry, aged four to seventeen.
The scans find eight spots in the genome tied to blood pressure and three tied to heart rate. Every spot is new for children, though adults studies had flagged them before. Scores built from the childhood genes predicted adult heart troubles in a national biobank, from high blood pressure to heart attacks. The childhood and adult gene effects overlap only partly. The authors argue that preventing heart disease may need to start with children's biology.
Catalog record
| CREATOR | Tian Xie, Alireza Ani, Ahmad Vaez, Ilja M Nolte, Shaoyong Su, Mami Ishikuro, Siqi Wang, Wenbo Zhang, Ana Goncalves Soares, Ehsan Motazedi, Lucinda Calas, Justiina Ronkainen, Casper-Emil T Pedersen, Xueling Lu, Sara E Stinson, Janine F Felix, Evelina Stankevic, Carol A Wang, Elisabeth Thiering, Dietm |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |