Multi-Criteria Decision Analysis using Physician Preferences from a Global Discrete Choice Experiment to Investigate the Selection of Preemptive Antiviral Treatments for Post-Hematopoietic Cell Transplant Cytomegalovirus Infection
Miguel-Angel Perales, Jo-Anne H Young, Tommi Tervonen, Stephane Deparis, Jonathan D Norton, Cristian Gugiu, Tien Bo, Kimberly Davis, ShunPing Quan, Victoria L Prince, Adel Abou Ali, Jessica Auciello · 2026
Read Multi-Criteria Decision Analysis using Physician Preferences from a Global Discrete Choice Experiment to Investigate the Selection of Preemptive Antiviral Treatments for Post-Hematopoietic Cell Transplant Cytomegalovirus Infection by Miguel-Angel Perales, Jo-Anne H Young, Tommi Tervonen, Stephane Deparis, Jonathan D Norton, Cristian Gugiu, Tien Bo, Kimberly Davis, ShunPing Quan, Victoria L Prince, Adel Abou Ali, Jessica Auciello (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13532088.txt.
Description
Miguel-Angel Perales and a team of co-authors asked doctors worldwide how they weigh drugs that pre-empt a common virus after stem cell transplant. The survey ran in 2026 and weighed gains against risks. The virus, called CMV, often wakes up after transplant, and several drugs can stop it early. Each drug trades benefit against harms such as kidney damage and low white cell counts.
In a choice survey, 377 doctors picked between made-up treatments again and again. How a drug is given and monitored mattered most, then kidney risk, white cell risk, and virus clearing by week eight. The team then fed those weights, plus real trial results, into a scoring model. One drug, maribavir, scored above its main rival in both patient groups split by white cell count at virus return.
Catalog record
| CREATOR | Miguel-Angel Perales, Jo-Anne H Young, Tommi Tervonen, Stephane Deparis, Jonathan D Norton, Cristian Gugiu, Tien Bo, Kimberly Davis, ShunPing Quan, Victoria L Prince, Adel Abou Ali, Jessica Auciello |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |