Mechanism study of miR-324-3p driving myocardial infarction progression through regulation of myocardial inflammation
Hongxia Liu, Wenjing Zhu, Wenzheng Wang, Ruishuang Tang · 2026
Read Mechanism study of miR-324-3p driving myocardial infarction progression through regulation of myocardial inflammation by Hongxia Liu, Wenjing Zhu, Wenzheng Wang, Ruishuang Tang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13531742.txt.
Description
Hongxia Liu and co-authors pinpoint in 2026 a tiny RNA that worsens heart attack injury by silencing a protective gene. Blood from 77 heart attack patients and 82 healthy people was compared, and rat heart cells underwent oxygen-starvation injury in the lab. The RNA, named miR-324-3p, rose sharply in patients.
Raising the RNA in injured cells fanned inflammation and stress, while blocking it calmed both. Its target gene STAT3 fell as the RNA rose. Removing STAT3 erased the benefit of blocking the RNA, proving the pairing drives the effect. The RNA also showed strong diagnostic value.
Catalog record
| CREATOR | Hongxia Liu, Wenjing Zhu, Wenzheng Wang, Ruishuang Tang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32460 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |