Implantable vagus nerve stimulation for the treatment of disorders of consciousness with epilepsy: a retrospective propensity score-matched clinical study

Jinyi Zuo, Kaiqiang Ma, Zizhang Cheng, Shu Wang, Xiongfei Wang, Weijin Sun, Junhong Pan, Xintao Peng, Wenlong Su, Haoran Zhang, Jian Zhou, Guoming Luan, Yuguang Guan · 2026

Read Implantable vagus nerve stimulation for the treatment of disorders of consciousness with epilepsy: a retrospective propensity score-matched clinical study by Jinyi Zuo, Kaiqiang Ma, Zizhang Cheng, Shu Wang, Xiongfei Wang, Weijin Sun, Junhong Pan, Xintao Peng, Wenlong Su, Haoran Zhang, Jian Zhou, Guoming Luan, Yuguang Guan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13530547.txt.

Description

Jinyi Zuo and co-authors studied, in a 2026 paper, whether an implanted vagus nerve stimulator helps patients who live with both a disorder of consciousness and epilepsy. Few therapies move such patients toward awareness. The device is standard for epilepsy but untested for this combined group.

Ninety patients either received the implant or were managed without it. Matching balanced the two arms at 23 patients each for the main comparison. After one year, about 35 percent of implanted patients had gained a meaningful step on a coma recovery scale, against 4 percent without. Gains in the implant group pulled ahead from month three onward. The authors present the result as a real signal for a group with almost no options, while noting the data are retrospective.

Catalog record

CREATORJinyi Zuo, Kaiqiang Ma, Zizhang Cheng, Shu Wang, Xiongfei Wang, Weijin Sun, Junhong Pan, Xintao Peng, Wenlong Su, Haoran Zhang, Jian Zhou, Guoming Luan, Yuguang Guan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13530547

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