Decoding regional keratinization in human oral mucosa through high-resolution spatial transcriptomics
Noy Rosental Vazani, Michal Lusthaus, Ana Caetano, Rami Khosravi, Avital Sarusi Portuguez, Carlos E Nemcovsky, Omer Bender, Daniel Z Bar, Miron Weinreb, Evgeny Weinberg · 2026
Read Decoding regional keratinization in human oral mucosa through high-resolution spatial transcriptomics by Noy Rosental Vazani, Michal Lusthaus, Ana Caetano, Rami Khosravi, Avital Sarusi Portuguez, Carlos E Nemcovsky, Omer Bender, Daniel Z Bar, Miron Weinreb, Evgeny Weinberg (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13530142.txt.
Description
Noy Rosental Vazani leads a 2026 mapping study of how mouth lining becomes tough and keratinized in some regions but stays soft in others. Tissue came from the border zone where gum meets cheek lining in two healthy donors. A high-resolution spatial method read gene activity spot by spot across each slice.
Sixteen tissue clusters mirrored the real anatomy and split gum from lining programs clearly. Both tissue fates branched from one shared starter layer. Collagen signals from supporting tissue engaged switches on surface cells, while strong cell-to-cell adhesion locks reinforced the tough program from within the surface layer itself.
Catalog record
| CREATOR | Noy Rosental Vazani, Michal Lusthaus, Ana Caetano, Rami Khosravi, Avital Sarusi Portuguez, Carlos E Nemcovsky, Omer Bender, Daniel Z Bar, Miron Weinreb, Evgeny Weinberg |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40240 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |