Poststroke fever etiology
Lijiang Wang, Wei Jin, Yuhua Wu, Menglu Zhu · 2026
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Description
Wang and colleagues reported a 2026 case in which fever after stroke turned out to be caused by the antibiotic rather than by a new infection. A 45-year-old woman with a brain infarction complicated by pneumonia linked to her stroke received piperacillin-tazobactam. During treatment she developed high fevers while her neutrophils, infection-fighting white blood cells, kept falling.
Wang describes a search for infectious and other causes pointed to drug fever combined with agranulocytosis. A drug-reaction scoring scale rated the link as probable. Agranulocytosis is a near-absence of neutrophils, and her lowest count fell to critically low levels. Stopping the antibiotic and giving a growth factor that boosts white cell production, plus adjusting other antimicrobials, resolved the fever and restored her counts. There was no recurrence over a year of follow-up. The authors urge blood monitoring during long courses of this antibiotic.
Catalog record
| CREATOR | Lijiang Wang, Wei Jin, Yuhua Wu, Menglu Zhu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |