Activated charcoal filtration profoundly alters systemic noradrenaline concentrations during hepatic chemosaturation: A prospective cohort study
Jan Turra, Dania Fischer, Osman Öcal, Oliver Biecker, Philipp Mayer, Philippe Grieshaber, Folker Wenzel, Matthias Karck, Marina Nikolic, Maik von der Forst, Markus Weigand, Hans-Ulrich Kauczor, Jessica Cecile Hassel, Christoph Lichtenstern, Maximilian Dietrich, Patrick Rehn, Jie Yang, Jie Yang, Jie · 2026
Read Activated charcoal filtration profoundly alters systemic noradrenaline concentrations during hepatic chemosaturation: A prospective cohort study by Jan Turra, Dania Fischer, Osman Öcal, Oliver Biecker, Philipp Mayer, Philippe Grieshaber, Folker Wenzel, Matthias Karck, Marina Nikolic, Maik von der Forst, Markus Weigand, Hans-Ulrich Kauczor, Jessica Cecile Hassel, Christoph Lichtenstern, Maximilian Dietrich, Patrick Rehn, Jie Yang, Jie Yang, Jie (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13528978.txt.
Description
Liver chemosaturation floods the liver with chemotherapy while filters scrub the blood leaving it, and the procedure swings patients' blood pressure wildly. Jan Turra and co-authors measured what the charcoal filter itself removes in 2026, across fifteen procedures.
Blood drawn before and after the filter told a sharp story. Noradrenaline, the body's own pressure-raising hormone and also a drug given during the procedure, rose steeply as the circuit ran. The charcoal filter then stripped about 95.5 percent of it in a single pass, even while infusions kept the dose high. Adrenaline and dopamine behaved differently. The authors warn that teams must plan around the filter eating the very drug that steadies the patient.
Catalog record
| CREATOR | Jan Turra, Dania Fischer, Osman Öcal, Oliver Biecker, Philipp Mayer, Philippe Grieshaber, Folker Wenzel, Matthias Karck, Marina Nikolic, Maik von der Forst, Markus Weigand, Hans-Ulrich Kauczor, Jessica Cecile Hassel, Christoph Lichtenstern, Maximilian Dietrich, Patrick Rehn, Jie Yang, Jie Yang, Jie |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 83 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |