Progesterone-induced endometrial thickness changes do not affect singleton neonatal outcomes in frozen embryo transfer: a retrospective analysis of 6,331 newborns
Jing Ye, Jie Zhang, Tong Du, Sha Yu, Yanwen Zhu, Hongyuan Gao, Yali Liu, Qiujiu Chen, Yanping Kuang · 2026
Read Progesterone-induced endometrial thickness changes do not affect singleton neonatal outcomes in frozen embryo transfer: a retrospective analysis of 6,331 newborns by Jing Ye, Jie Zhang, Tong Du, Sha Yu, Yanwen Zhu, Hongyuan Gao, Yali Liu, Qiujiu Chen, Yanping Kuang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13528165.txt.
Description
Jing Ye and eight colleagues check whether womb lining changes during hormone treatment affect babies from frozen embryo transfer in a 2026 study. The records held 6,331 single babies born after day-three frozen transfers. Ultrasound measured lining thickness before progesterone and on transfer day. Babies were grouped by whether the lining grew, shrank, or stayed flat.
Mean birth weights were nearly identical across the three groups, around 3,350 grams. Low birth weight rates did not rise when the lining shrank. Small-for-dates rates also matched. Adjustment for other factors kept the picture flat. Baby sex and pregnancy length did move birth weight, as expected. The authors conclude lining wiggles after progesterone are not a warning sign. Clinics need not cancel cycles over them, they say.
Catalog record
| CREATOR | Jing Ye, Jie Zhang, Tong Du, Sha Yu, Yanwen Zhu, Hongyuan Gao, Yali Liu, Qiujiu Chen, Yanping Kuang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47291 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |