Co-development of a protocol for a randomised controlled feasibility trial of CIRCuiTS™ cognitive remediation therapy for people with multiple sclerosis
Rebecca J Thomas, Matteo Cella, Peter A Brex, Eli Silber, Kate Fifield, Patrick Burke, Mary Summers, Sara Simblett, Til Wykes · 2026
Read Co-development of a protocol for a randomised controlled feasibility trial of CIRCuiTS™ cognitive remediation therapy for people with multiple sclerosis by Rebecca J Thomas, Matteo Cella, Peter A Brex, Eli Silber, Kate Fifield, Patrick Burke, Mary Summers, Sara Simblett, Til Wykes (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13527947.txt.
Description
Rebecca J. Thomas and eight colleagues describe in 2026 how people with multiple sclerosis helped design a feasibility trial of CIRCuiTS, a computer-based cognitive remediation program delivered with a therapist. Thinking problems are common in MS and drag down quality of life, yet proven treatments are scarce.
Consultation ran in three phases, including a two-day workshop that produced 24 practical recommendations. The planned trial will recruit 24 people with MS and cognitive difficulties from a UK health service, giving half the twelve-week program at once and half after a thirteen-week wait. Sessions can be remote and adapted for dexterity problems. Feasibility and acceptability come first, with goals, cognition, fatigue, and mood also tracked.
Catalog record
| CREATOR | Rebecca J Thomas, Matteo Cella, Peter A Brex, Eli Silber, Kate Fifield, Patrick Burke, Mary Summers, Sara Simblett, Til Wykes |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49729 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |