Synergistic Combination of Cryptolepis sanguinolenta (Lindl.) Schlechter (Apocynaceae) and Azadirachta Indica (A. Juss) (Meliaceae) Against 3D7 and DD2 Strains of Plasmodium Falciparum
Samuel Korsah, Nathaniel Nene Djangmah Nortey, Christian Akakpo, Felix Kwame Zoiku, Jessica Korsah, Miriam Tagoe, Joseph Kwao Amanor, Babu Jacob Yamba, Josephine Akosua Ofori-Asamoah · 2026
Read Synergistic Combination of Cryptolepis sanguinolenta (Lindl.) Schlechter (Apocynaceae) and Azadirachta Indica (A. Juss) (Meliaceae) Against 3D7 and DD2 Strains of Plasmodium Falciparum by Samuel Korsah, Nathaniel Nene Djangmah Nortey, Christian Akakpo, Felix Kwame Zoiku, Jessica Korsah, Miriam Tagoe, Joseph Kwao Amanor, Babu Jacob Yamba, Josephine Akosua Ofori-Asamoah (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13527865.txt.
Description
Samuel Korsah led a team testing two Ghanaian medicinal plants together against malaria in a 2026 paper. The two herbs are often blended in local products for the disease. In lab dishes, water extracts of each were tested against a drug-sensitive malaria parasite strain and a resistant one. Software judged whether the pair merely added up or truly reinforced each other.
Each extract alone was strongly active against both strains. Together they showed clear synergy, with combination scores well below the additive line across most effect levels. Doses needed also dropped in combination. The authors conclude the traditional pairing is better supported than either herb used alone.
Catalog record
| CREATOR | Samuel Korsah, Nathaniel Nene Djangmah Nortey, Christian Akakpo, Felix Kwame Zoiku, Jessica Korsah, Miriam Tagoe, Joseph Kwao Amanor, Babu Jacob Yamba, Josephine Akosua Ofori-Asamoah |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |