Temporal Inflammatory Profile in Skin Surface after Oronasal Mask Application
Amanda Feldt, William Lövfors, Elin Nyman, Peter R. Worsley, Bijar Ghafouri, Sara Bergstrand · 2026
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Description
Amanda Feldt and five co-authors tracked the skin's inflammatory response in the hours after a breathing mask comes off. Mask pressure can start pressure ulcers before any redness shows, and the early chemistry of that process is poorly known. The team collected sebum samples from eleven patients at six times over three hours after mask removal and measured seventy-one inflammatory proteins.
The response came in two waves: a quick phase in the first twenty minutes and a delayed phase running from forty minutes to three hours, separated by seventeen proteins. The delayed wave stayed elevated even though the skin looked normal, a sign of hidden, ongoing irritation. Protein networks pointed to vessel growth, cell death control, and tissue remodeling, the hallmarks of early wound response. The authors say the timing map can guide when to sample biomarkers and help design sensors that warn before damage appears.
Catalog record
| CREATOR | Amanda Feldt, William Lövfors, Elin Nyman, Peter R. Worsley, Bijar Ghafouri, Sara Bergstrand |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |