Reversal of surgical biliary diversion with ileal bile acid transport inhibitors: A new chapter in progressive familiar intrahepatic cholestasis type 1 management?
Teresa Botelho, Giulia Jannone, Roberto Tambucci, Catherine de Magnee, Isabelle Scheers, Etienne Sokal, Xavier Stephenne · 2026
Read Reversal of surgical biliary diversion with ileal bile acid transport inhibitors: A new chapter in progressive familiar intrahepatic cholestasis type 1 management? by Teresa Botelho, Giulia Jannone, Roberto Tambucci, Catherine de Magnee, Isabelle Scheers, Etienne Sokal, Xavier Stephenne (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13527563.txt.
Description
Teresa Botelho and co-authors report the case of one patient, in a piece from 2026. It deals with reversal of surgical biliary diversion in progressive familial intrahepatic cholestasis type one. That disorder hits more than one body system, not the liver alone.
The patient had a liver transplant, and then got protein-losing enteropathy. At first, surgical biliary diversion was used to deal with it. That surgery helped, but it caused severe fat malabsorption. The patient then needed lipid support given by vein. Care with an ileal bile acid transport inhibitor let surgeons reverse the diversion. The enteropathy did not come back. The team puts the drug class forth as a choice that could stand in for diversion. They also see it as a way to undo past surgery and lift quality of life.
Catalog record
| CREATOR | Teresa Botelho, Giulia Jannone, Roberto Tambucci, Catherine de Magnee, Isabelle Scheers, Etienne Sokal, Xavier Stephenne |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |