Comment on “The Diagnostic Performance of the AlzoSure Predict Assay and Its Association With Alzheimer's Disease Biomarkers and Imaging Findings”
Muhammad Ahmad Khan, Nida Sher · 2026
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Description
Khan and Sher write a letter about a study of the AlzoSure Predict blood test for Alzheimer's disease, which measures a folded form of the protein p53. They praise the study for testing the assay against spinal fluid markers, but they raise points that qualify what the test can claim. Their letter is a comment and reports no new data.
They note that the study never tested whether spinal fluid tau markers add value on top of the blood markers already known. Nor did it compare the assay head-to-head with the strong plasma tau tests now in use, or run the standard added-value statistics. The comparison also covered only healthy people against those with mild impairment, not the full clinic population. Until such checks are done, they argue, it stays unclear whether the assay adds anything beyond what existing markers already show.
Catalog record
| CREATOR | Muhammad Ahmad Khan, Nida Sher |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 4 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |