Patient‐Specific Computational Fluid Dynamics Modeling of Airway Collapse in Infants With Robin Sequence
Gautam Jalori, Michael Barbour, Michael Bindschadler, Kelly Evans, Jake Dahl, Alberto Aliseda · 2026
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Description
Gautam Jalori and co-authors build, in twenty twenty-six, patient-specific computer models of airway collapse in infants with Robin Sequence. In this birth condition, an underdeveloped jaw and a backward tongue cause the upper airway to obstruct or collapse in cycles. Clinical checks give no hard numbers and miss the dynamic behavior. Their method extracts airway motion from four-dimensional CT scans. It then runs a moving-mesh fluid dynamics analysis for patients with complete collapse. Airflow is graded by instant measures, velocity, pressure, and energy loss, plus cycle-averaged breathing work.
The collapsing airway was compared with a synthetic non-collapsing twin. To reach the same air volume, the collapsing case needed about double the computed breathing effort. A real non-collapsing patient validated the synthetic control.
Catalog record
| CREATOR | Gautam Jalori, Michael Barbour, Michael Bindschadler, Kelly Evans, Jake Dahl, Alberto Aliseda |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |