Thrombus Metabolism‐Based Molecular Subtyping for Prognostic Risk Stratification in Acute Ischemic Stroke: A Preliminary Study
Taoyuan Lu, Wei Li, Wenbo Cao, Yiying Liu, Jinzi Wei, Dechao Wang, Liqun Jiao, Xin Xu · 2026
Read Thrombus Metabolism‐Based Molecular Subtyping for Prognostic Risk Stratification in Acute Ischemic Stroke: A Preliminary Study by Taoyuan Lu, Wei Li, Wenbo Cao, Yiying Liu, Jinzi Wei, Dechao Wang, Liqun Jiao, Xin Xu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13526402.txt.
Description
Lu and co-authors sort stroke-causing blood clots into metabolic subtypes, in a 2026 preliminary study. The clots were pulled from 36 patients with large vessel blockages in the front of the brain. Chemical profiling of the clot tissue searched for patterns tied to recovery. Unsupervised clustering split the clots into two groups based on twelve small molecules.
One subtype, mostly from heart-source clots, showed richer fat metabolism and worse brain damage on arrival, with poorer recovery at one week and ninety days. The other, mostly from artery plaque clots, leaned on folate metabolism. A six-molecule signature could separate the subtypes and hint at outcomes. The authors frame clot chemistry as a new window on stroke prognosis, pending larger studies.
Catalog record
| CREATOR | Taoyuan Lu, Wei Li, Wenbo Cao, Yiying Liu, Jinzi Wei, Dechao Wang, Liqun Jiao, Xin Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |