Acquired Hemophilia A in an Elderly Patient Receiving Clopidogrel: Drug-Induced or Age-Associated Autoimmunity?
Akhil Mohanachandran Pushpaleela, Rahil Omar Tai Valappil, Ayshath Hansiya, Siobhan Lewis · 2026
Read Acquired Hemophilia A in an Elderly Patient Receiving Clopidogrel: Drug-Induced or Age-Associated Autoimmunity? by Akhil Mohanachandran Pushpaleela, Rahil Omar Tai Valappil, Ayshath Hansiya, Siobhan Lewis (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13526308.txt.
Description
Pushpaleela and colleagues report a 2026 case of acquired hemophilia A in a 93-year-old man taking clopidogrel, a blood-thinning drug. The rare autoimmune disorder makes antibodies that attack factor VIII, a protein needed for clotting, and it can cause sudden heavy bruising and bleeding in older adults.
His tests showed a prolonged clotting time, low factor VIII activity, and factor VIII inhibitors, confirming the diagnosis. Hematology specialists directed treatment, but his course grew complicated and he died. The authors weigh whether clopidogrel or age-related autoimmunity triggered the condition. They urge doctors to suspect acquired hemophilia A quickly in older patients with unexplained bleeding, since delays raise the risk of death.
Catalog record
| CREATOR | Akhil Mohanachandran Pushpaleela, Rahil Omar Tai Valappil, Ayshath Hansiya, Siobhan Lewis |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 10 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |