Circulating pTau181 and Genomic Background in Dogs: A Pilot Study on Neurobiological Aging
Valentina Gazzano, Maria Chiara Fabbri, Simona Capsoni, Carlo Cantile, Lara Tinacci, Angelo Gazzano, Maria Claudia Curadi, Francesca Cecchi, Lipi Buch · 2026
Read Circulating pTau181 and Genomic Background in Dogs: A Pilot Study on Neurobiological Aging by Valentina Gazzano, Maria Chiara Fabbri, Simona Capsoni, Carlo Cantile, Lara Tinacci, Angelo Gazzano, Maria Claudia Curadi, Francesca Cecchi, Lipi Buch (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13526283.txt.
Description
Valentina Gazzano and co-authors pilot a blood marker of brain aging in dogs in a 2026 study. Dogs age much like humans at the molecular level, making them a useful mirror. Forty-eight dogs, Labradors and mixed breeds aged two to fifteen, give blood for phosphorylated tau 181, a marker tied to nerve decay. Genome scans map breed structure and inbreeding alongside.
The marker shows a measurable signal in all dogs, they report. Levels do not track age, sex, or breed group in this small sample. Labradors show far more genomic sameness than mixed breeds. Marker levels ignore inbreeding scores. One weak gene link appears, flagged as exploratory only.
Catalog record
| CREATOR | Valentina Gazzano, Maria Chiara Fabbri, Simona Capsoni, Carlo Cantile, Lara Tinacci, Angelo Gazzano, Maria Claudia Curadi, Francesca Cecchi, Lipi Buch |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |