Combination Treatment of Docetaxel Liposomes and Sonodynamic Therapy With Verteporfin Liposomes in Patients With Cancer: A Report of Three Cases
Yasuo Komura, Shintarou Kimura, Yumi Hirasawa, Ryo Takasaki, Saki Fukuro, Nguyen Thi Mai Thi, Miyaji Gengou, Lee Sang Woo, Osamu Imataki, Toru Yanagawa, Koichiro Homma · 2026
Read Combination Treatment of Docetaxel Liposomes and Sonodynamic Therapy With Verteporfin Liposomes in Patients With Cancer: A Report of Three Cases by Yasuo Komura, Shintarou Kimura, Yumi Hirasawa, Ryo Takasaki, Saki Fukuro, Nguyen Thi Mai Thi, Miyaji Gengou, Lee Sang Woo, Osamu Imataki, Toru Yanagawa, Koichiro Homma (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13526248.txt.
Description
Yasuo Komura and co-authors (2026) report three cancer patients treated with a new drug and sound combination. The treatment pairs liposome-wrapped docetaxel, a drug that blocks cell division, with sonodynamic therapy: a second wrapped drug, verteporfin, gathers in tumors and kills cells when ultrasound is applied. Wrapping both drugs in fat bubbles helps them collect in tumor tissue. The patients had ovarian spread of stomach cancer, advanced stomach cancer, and lung spread of breast cancer.
All three showed strong tumor control without notable side effects. The first and third patients had kept growing worse through earlier chemotherapy and immune therapy, yet this treatment halted the advance. The second patient was judged too old for standard options and still benefited. The authors call this the first clinical report of the three-part combination and present it as a promising, gentle option that needs larger trials.
Catalog record
| CREATOR | Yasuo Komura, Shintarou Kimura, Yumi Hirasawa, Ryo Takasaki, Saki Fukuro, Nguyen Thi Mai Thi, Miyaji Gengou, Lee Sang Woo, Osamu Imataki, Toru Yanagawa, Koichiro Homma |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |