Evaluation of Preventive Antibiotic Regimens for Preterm Premature Rupture of Membranes: Efficacy and Safety of Triple Therapy versus Cephalosporin Monotherapy
Chenjie Luo, Caihua Yang, Tianyue Zhou, Ping Zheng, Taoyan Lin, Xiangying Deng, Chao Sheng, Yilei Li · 2026
Read Evaluation of Preventive Antibiotic Regimens for Preterm Premature Rupture of Membranes: Efficacy and Safety of Triple Therapy versus Cephalosporin Monotherapy by Chenjie Luo, Caihua Yang, Tianyue Zhou, Ping Zheng, Taoyan Lin, Xiangying Deng, Chao Sheng, Yilei Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13526170.txt.
Description
Luo and seven co-authors compare two antibiotic plans for pregnant women whose waters break early, in this two thousand twenty-six study. When the membranes rupture before term, preventive antibiotics guard mother and baby against infection, but the best recipe is debated.
At one Chinese hospital, thirty-two women received a triple plan of a cephalosporin plus azithromycin and clindamycin, while sixty received the cephalosporin alone. After statistical adjustment, the main outcomes for mothers and newborn breathing problems did not differ significantly. Triple therapy did link to lower rates of a chronic lung problem and brain bleeding in babies in exploratory analyses, and longer pregnancies in one subgroup. The authors treat these hints cautiously given the small numbers.
Catalog record
| CREATOR | Chenjie Luo, Caihua Yang, Tianyue Zhou, Ping Zheng, Taoyan Lin, Xiangying Deng, Chao Sheng, Yilei Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |