Are liver metastases from uveal melanoma a clinical indication for dynamic PET? A comparison of Patlak parametric imaging with standard and delayed static SUV imaging using long axial field-of-view PET/CT
Leyun Pan, Christos Sachpekidis, Dimitrios S Strauss, Jessica C Hassel, Antonia Dimitrakopoulou-Strauss · 2026
Read Are liver metastases from uveal melanoma a clinical indication for dynamic PET? A comparison of Patlak parametric imaging with standard and delayed static SUV imaging using long axial field-of-view PET/CT by Leyun Pan, Christos Sachpekidis, Dimitrios S Strauss, Jessica C Hassel, Antonia Dimitrakopoulou-Strauss (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13526073.txt.
Description
Leyun Pan and colleagues ask, in a 2026 prospective study, whether dynamic PET imaging adds value for liver metastases from uveal melanoma. This eye cancer's liver spread can be faint on standard scans. Dynamic imaging tracks tracer movement over an hour and builds parametric maps, yet technical complexity has kept it from routine oncology use.
Twenty-six patients with 126 lesions, including 58 liver metastases, underwent an hour-long dynamic scan plus a later whole-body scan on a long-field scanner. Three image sets were compared, parametric maps, standard static images, and delayed static images. Total lesion detection did not differ significantly between approaches. One true liver metastasis appeared on the parametric map and was confirmed by MRI after being unclear on static images. Quantitative contrast ratios were measured for every lesion.
Catalog record
| CREATOR | Leyun Pan, Christos Sachpekidis, Dimitrios S Strauss, Jessica C Hassel, Antonia Dimitrakopoulou-Strauss |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35737 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |