Impact of CPAP and ventilator system resistance on respiratory effort in healthy volunteers
Simon Lindner, Lena Doerflinger, Luisa S Drotleff, Burcu Link, Benjamin Neetz, Julia D Michels-Zetsche, Felix J F Herth, Daniel Duerschmied, Simone Britsch · 2026
Read Impact of CPAP and ventilator system resistance on respiratory effort in healthy volunteers by Simon Lindner, Lena Doerflinger, Luisa S Drotleff, Burcu Link, Benjamin Neetz, Julia D Michels-Zetsche, Felix J F Herth, Daniel Duerschmied, Simone Britsch (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13525642.txt.
Description
Simon Lindner and co-authors measure how breathing machines themselves load the breath of healthy volunteers, in a 2026 study. Steady pressure support, CPAP, is a workhorse for failing lungs, and a boost on each breath turns it into fuller ventilation. Thirty-eight volunteers breathed under four settings, from plain air to both supports, at rest and under light and hard exercise. A thin throat sensor read the effort in each swing.
At rest, plain CPAP asked the most effort of all, more than free air or the boosted mode. Under exercise, both the bare ventilator and CPAP raised effort above free air and boosted breathing. The authors blame the machine's own resistance, which bites harder as air flow climbs. Since failing lungs often drive fast, deep breathing, they urge trials of what this load means for patients.
Catalog record
| CREATOR | Simon Lindner, Lena Doerflinger, Luisa S Drotleff, Burcu Link, Benjamin Neetz, Julia D Michels-Zetsche, Felix J F Herth, Daniel Duerschmied, Simone Britsch |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |