An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development
Rajnish Kumar, Purbasa Dasgupta, Soma Ray, Soumen Paul · 2026
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Description
Rajnish Kumar and co-authors hunt for key kinases in placenta development in a 2026 paper. Three trophoblast cell types build the working placenta during pregnancy. Each type has a distinct job, and all three are needed for a healthy outcome.
Stem-like cells feed the other two types as they mature over time. One type forms the exchange surface with maternal blood and makes a key pregnancy hormone. The other invades uterine tissue and anchors the placenta in place. Human trophoblast stem cells served as the lab model for the work. Protein and gene data were combined to find essential kinases. Readers learn which signaling enzymes a healthy placenta cannot do without.
Catalog record
| CREATOR | Rajnish Kumar, Purbasa Dasgupta, Soma Ray, Soumen Paul |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |