Artificial Intelligence‐Estimated Intrapancreatic Fat and Its Relationship to Familial and Germline Pancreatic Cancer Risk

Tom Konikoff, Laurens P Janssens, Hiroaki Takahashi, Garima Suman, Fred Nugen, Anup Mishra, Panos Korfiatis, Erin E Carlson, William R Bamlet, Aishwarya Pradeep, Kelly Harper, Karen A Doering, Adriana Delgado, Bradley J Erickson, Ajit H Goenka, Naoki Takahashi, Ann L Oberg, Shounak Majumder · 2026

Read Artificial Intelligence‐Estimated Intrapancreatic Fat and Its Relationship to Familial and Germline Pancreatic Cancer Risk by Tom Konikoff, Laurens P Janssens, Hiroaki Takahashi, Garima Suman, Fred Nugen, Anup Mishra, Panos Korfiatis, Erin E Carlson, William R Bamlet, Aishwarya Pradeep, Kelly Harper, Karen A Doering, Adriana Delgado, Bradley J Erickson, Ajit H Goenka, Naoki Takahashi, Ann L Oberg, Shounak Majumder (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13525327.txt.

Description

Tom Konikoff and co-authors report a 2026 study on fat inside the pancreas and the risk of pancreatic cancer. Family history and certain inherited gene changes each raise the risk of this cancer. Fat in the pancreas may raise it too, but whether high-risk people carry more of that fat was unknown.

The team built a deep learning tool that outlines the whole pancreas on MRI scans and measures its fat share. Standard methods sample only small regions, which can mislead because the fat is spread unevenly. The tool lets the authors compare high-risk people with matched controls on equal terms. The study sets up a fair test of whether pancreatic fat marks higher risk.

Catalog record

CREATORTom Konikoff, Laurens P Janssens, Hiroaki Takahashi, Garima Suman, Fred Nugen, Anup Mishra, Panos Korfiatis, Erin E Carlson, William R Bamlet, Aishwarya Pradeep, Kelly Harper, Karen A Doering, Adriana Delgado, Bradley J Erickson, Ajit H Goenka, Naoki Takahashi, Ann L Oberg, Shounak Majumder
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13525327

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