Development and validation of a broadly cross-reactive polyclonal antibody as capture antibody for pan human β coronavirus antigen detection
Qiang Wu, Zhan-Zhao Wang, Zhen-Ming Wang, Yu-Hui Wang · 2026
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Description
Qiang Wu and co-authors develop a broad antibody for detecting human beta coronaviruses in a 2026 study. This virus group causes airway illness, and antigen tests can aid diagnosis. A single capture antibody that spots five members at once would simplify such tests.
The team built a shared peptide from the viruses' shell protein, raised antibodies in rabbits, and purified the best serum. Test formats confirmed the antibody captures the shell proteins of all five viruses. Throat swabs from infected patients checked real-world capture. A pan-group test could help clinics screen quickly when a new member of the family appears.
Catalog record
| CREATOR | Qiang Wu, Zhan-Zhao Wang, Zhen-Ming Wang, Yu-Hui Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |