Elevation of body temperature during exercise enhances protection against dexamethasone‑induced skeletal muscle atrophy

Berkay Ozerklig, Senay Akin, Seda Olgaz Bingol, Bulent Okan Yildiz, Scott K. Powers, Ibrahim Turkel, Haydar A. Demirel · 2026

Read Elevation of body temperature during exercise enhances protection against dexamethasone‑induced skeletal muscle atrophy by Berkay Ozerklig, Senay Akin, Seda Olgaz Bingol, Bulent Okan Yildiz, Scott K. Powers, Ibrahim Turkel, Haydar A. Demirel (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13524206.txt.

Description

Berkay Ozerklig and six co-authors published a muscle physiology study in twenty twenty-six on whether the heat of exercise protects muscle during steroid treatment. Long glucocorticoid use wastes muscle by cutting protein building and raising breakdown. Exercise helps, but the team suspected body temperature itself does part of the work.

Forty-eight rats were split into six groups combining the steroid dexamethasone with exercise in cold or warm rooms. The steroid shrank muscle mass and fiber size sharply. Cold-room exercise protected only partly. Warm-room exercise fully preserved mass and fiber size, beating the steroid-only group clearly. The result suggests warming up is not just comfort; it is part of the medicine.

Catalog record

CREATORBerkay Ozerklig, Senay Akin, Seda Olgaz Bingol, Bulent Okan Yildiz, Scott K. Powers, Ibrahim Turkel, Haydar A. Demirel
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13524206

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