Sophocarpine Alleviates Airway Epithelial Cell Inflammation in Asthma via Modulating the Cytokine- Cytokine Receptor and JAK2/STAT3 Signaling Pathways
Wenbing Zhi, Hong Zhang, Ziyao Qiao, Shengnan Jiang, Zongsuo Liang, Yang Liu · 2026
Read Sophocarpine Alleviates Airway Epithelial Cell Inflammation in Asthma via Modulating the Cytokine- Cytokine Receptor and JAK2/STAT3 Signaling Pathways by Wenbing Zhi, Hong Zhang, Ziyao Qiao, Shengnan Jiang, Zongsuo Liang, Yang Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13523874.txt.
Description
Wenbing Zhi and five co-authors test, in 2026 work, a plant compound as a treatment for asthma in mice and cells. Asthma swells and narrows the airways, and its rates keep rising around the world. The team built the illness with house dust mite extract, a common trigger.
The compound eased lung damage and mucus, and cut a set of swelling signals and allergy marks in the mice. Computer and gene reads pointed to a few key targets and to two signal paths that drive swelling. In cells, the compound also kept airway cells alive and cut stress damage. Blocking one key target gave like effects. The team reads this as proof the compound calms airway swelling through those paths.
Catalog record
| CREATOR | Wenbing Zhi, Hong Zhang, Ziyao Qiao, Shengnan Jiang, Zongsuo Liang, Yang Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |