Extraction solvent shapes the phytochemistry, multi-target bioactivity, and machine learning-predicted anticancer targets of Seseli libanotis
Mehmet Veysi Cetiz, Abdullahi Ibrahim Uba, Milena Terzic, Josef Jeko, Zsolt Szilágyi, Ulku Yerebasan, Ismail Koyuncu, Ozgur Yuksekdag, Sakina Yagi, Gokhan Zengin · 2026
Read Extraction solvent shapes the phytochemistry, multi-target bioactivity, and machine learning-predicted anticancer targets of Seseli libanotis by Mehmet Veysi Cetiz, Abdullahi Ibrahim Uba, Milena Terzic, Josef Jeko, Zsolt Szilágyi, Ulku Yerebasan, Ismail Koyuncu, Ozgur Yuksekdag, Sakina Yagi, Gokhan Zengin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13523778.txt.
Description
Mehmet Cetiz and co-authors test how the fluid used to pull chemicals from a wild herb shifts what the extract can do, in a study from 2026. The herb is eaten as a green in eastern Anatolia, but its deep chemistry was thinly known. Four fluids of mixed strength drew extracts from the above ground parts for a full round of lab checks.
The mixed alcohol and water draw held the most plant phenols and hit tumor cells hardest in dish tests. Plain water led on three guard tests, while each fluid won on some enzyme blocks. Computer fits tied plant chemicals to enzyme pockets in stable poses. Yet the best draw also harmed healthy kidney cells, so its tumor aim is weak. The fluid choice ruled the whole profile.
Catalog record
| CREATOR | Mehmet Veysi Cetiz, Abdullahi Ibrahim Uba, Milena Terzic, Josef Jeko, Zsolt Szilágyi, Ulku Yerebasan, Ismail Koyuncu, Ozgur Yuksekdag, Sakina Yagi, Gokhan Zengin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 86 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |