Whole genome analysis of a multidrug-resistant blaNDM−5-carrying Escherichia coli Sequence Type (ST) 167 strain isolated from seafood in Mumbai, India
Chandrashekar K. Dhanush, Ramanath Prerana, Manjusha Lekshmi, Sanath H. Kumar · 2026
Read Whole genome analysis of a multidrug-resistant blaNDM−5-carrying Escherichia coli Sequence Type (ST) 167 strain isolated from seafood in Mumbai, India by Chandrashekar K. Dhanush, Ramanath Prerana, Manjusha Lekshmi, Sanath H. Kumar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13523529.txt.
Description
Chandrashekar K. Dhanush and others report a 2026 whole genome analysis of a multidrug-resistant E. coli strain taken from seafood in Mumbai, India. The strain belongs to sequence type 167, an emerging clone that can cause infections outside the gut. It carries a gene, blaNDM-5, that confers resistance to last-resort carbapenem antibiotics.
Lab testing showed resistance to 26 of 33 antibiotics tried, matching predictions from the genome. Sequencing placed the strain in serotype O101:H9 and phylogroup A, and it carried many virulence genes suggesting potential to harm humans. Resistance genes covered several drug classes, and mutations explained quinolone resistance. The authors warn that fecal contamination of seafood can spread such resistant clones through the community and call for monitoring of the supply chain.
Catalog record
| CREATOR | Chandrashekar K. Dhanush, Ramanath Prerana, Manjusha Lekshmi, Sanath H. Kumar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29010 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |