Islet autoantibodies as predictors of type 1 diabetes development, a systematic review with public health implications for Africa
Babatunde Ishola Gabriel Adejumo, Afolabi Adiru Adegboye, Folorunso Lawrence Dada, Margaret Oyarazi Adebowale, Fidelis Ohiremen Oyakhire, Grace Ayobami Fajemidagba, Mariachidera Angela Obiajunwa, Nkechi Augustina Olise, Olufunke Deborah Abolarin, Emmanuel Olawale Ogunmola, Uteno Itanyi Drisu, Nnagbo Nonso Udemezue, Otiogha Udogidi Erowo, Ronke Funmilayo Ajiboye, Kenneth Echezona Ilekuba, Lilian Weremenesongha Agindoton · 2026
Read Islet autoantibodies as predictors of type 1 diabetes development, a systematic review with public health implications for Africa by Babatunde Ishola Gabriel Adejumo, Afolabi Adiru Adegboye, Folorunso Lawrence Dada, Margaret Oyarazi Adebowale, Fidelis Ohiremen Oyakhire, Grace Ayobami Fajemidagba, Mariachidera Angela Obiajunwa, Nkechi Augustina Olise, Olufunke Deborah Abolarin, Emmanuel Olawale Ogunmola, Uteno Itanyi Drisu, Nnagbo Nonso Udemezue, Otiogha Udogidi Erowo, Ronke Funmilayo Ajiboye, Kenneth Echezona Ilekuba, Lilian Weremenesongha Agindoton (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13523443.txt.
Description
Babatunde Ishola Gabriel Adejumo leads a large author group in a 2026 systematic review on whether islet autoantibodies can predict who will develop type 1 diabetes, with special attention to Africa. These antibodies signal immune attack on insulin-producing beta cells. Early identification of high-risk people is a public health priority, yet evidence from African populations has rarely been gathered together.
Following PRISMA 2020 guidance, the team searched four major databases for studies from 2000 to 2026 and included 47 studies in qualitative synthesis. Eight addressed African populations or African diabetes patterns, and a smaller comparable subset entered quantitative pooling. Across studies, higher antibody levels and positivity for several antibodies at once were consistently linked with later disease. The review discusses what screening would require in African health systems.
Catalog record
| CREATOR | Babatunde Ishola Gabriel Adejumo, Afolabi Adiru Adegboye, Folorunso Lawrence Dada, Margaret Oyarazi Adebowale, Fidelis Ohiremen Oyakhire, Grace Ayobami Fajemidagba, Mariachidera Angela Obiajunwa, Nkechi Augustina Olise, Olufunke Deborah Abolarin, Emmanuel Olawale Ogunmola, Uteno Itanyi Drisu, Nnagbo Nonso Udemezue, Otiogha Udogidi Erowo, Ronke Funmilayo Ajiboye, Kenneth Echezona Ilekuba, Lilian Weremenesongha Agindoton |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 99403 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |