Comparing the clinical pregnancy outcomes of fresh embryo transfer in young patients with poor prognosis using different ovarian stimulation protocols
Nan Jia, Ruolei Wang, Qiuyuan Li, Haoying Hao, Siyue Xu, Lei Jin, Yundong Mao, Juanzi Shi, Cuilian Zhang, Xiaoyan Liang, Shaodi Zhang · 2026
Read Comparing the clinical pregnancy outcomes of fresh embryo transfer in young patients with poor prognosis using different ovarian stimulation protocols by Nan Jia, Ruolei Wang, Qiuyuan Li, Haoying Hao, Siyue Xu, Lei Jin, Yundong Mao, Juanzi Shi, Cuilian Zhang, Xiaoyan Liang, Shaodi Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13523388.txt.
Description
Nan Jia and co-authors compare two ovarian stimulation protocols ahead of fresh transfer in younger patients whose outlook is poor, in a 2026 retrospective study. Women under thirty-five with low ovarian reserve marker levels were drawn from fertility treatment records spanning 2016 to 2024. Nearly five thousand cycles were compared, then matched one to one to balance the groups before further analysis.
After matching, the agonist protocol produced a higher clinical pregnancy rate and a notably higher live birth rate than the antagonist protocol. Ectopic pregnancy, early miscarriage, and preterm birth did not differ clearly. The agonist group also had fewer cancelled fresh transfers and fewer cycles ending in freezing all embryos. Adjusted analysis confirmed both advantages, supporting the agonist approach for this specific patient group.
Catalog record
| CREATOR | Nan Jia, Ruolei Wang, Qiuyuan Li, Haoying Hao, Siyue Xu, Lei Jin, Yundong Mao, Juanzi Shi, Cuilian Zhang, Xiaoyan Liang, Shaodi Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36302 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |