Stage migration and prognostic refinement of oral squamous cell carcinoma under the AJCC 8th edition staging system: a retrospective cohort study with additional evaluation using the SEER database
Jianing Cui, Qianrui Liu, Hongshi Cai, Jianfeng Liang, Hongyu Li, Yue Zhu, Meng Xu, Jinsong Hou · 2026
Read Stage migration and prognostic refinement of oral squamous cell carcinoma under the AJCC 8th edition staging system: a retrospective cohort study with additional evaluation using the SEER database by Jianing Cui, Qianrui Liu, Hongshi Cai, Jianfeng Liang, Hongyu Li, Yue Zhu, Meng Xu, Jinsong Hou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13523358.txt.
Description
Jianing Cui and collaborators test a revised cancer staging edition for mouth cancer in a 2026 retrospective cohort study with an external database check. The eighth edition staging system added tumor invasion depth and spread beyond lymph node capsules to the classification. Patient data came from a university hospital cohort treated between 2014 and 2021 and from a large United States registry.
About three in ten patients were upstaged under the new edition. In the hospital cohort the new system separated survival between middle and advanced tumor categories more clearly than the old one, although the two earliest categories still overlapped. In the registry cohort, separation at the same boundary stayed weak. The authors propose a refined tumor classification based on their cohort and evaluate it against established criteria for staging quality.
Catalog record
| CREATOR | Jianing Cui, Qianrui Liu, Hongshi Cai, Jianfeng Liang, Hongyu Li, Yue Zhu, Meng Xu, Jinsong Hou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53958 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |