Brain metastatic paraganglioma from liver: a case report and review of the literature
Hongwei Zhang, Xiaolong Qiao, Zixuan Wang, Qin Li, Chuandong Cheng · 2026
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Description
Hongwei Zhang and colleagues report a rare tumor that spread from liver to brain in a 2026 case report with a literature review. A fifty-two-year-old woman presented with headache lasting over a month. Years earlier she had surgery for a liver mass confirmed as paraganglioma, a rare hormone-related tumor that is usually benign yet can occasionally spread.
Brain tissue removed in a later operation showed changes in three genes and confirmed metastatic paraganglioma of a low-oxygen-driven subtype. Chemotherapy with temozolomide left no sign of brain recurrence at the last check reported, although enlarged lymph nodes and suspicious lesions appeared elsewhere in the body. The authors detail the clinical, imaging, tissue, and molecular features to raise awareness of this uncommon presentation.
Catalog record
| CREATOR | Hongwei Zhang, Xiaolong Qiao, Zixuan Wang, Qin Li, Chuandong Cheng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28185 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |