Recurrent optic neuritis as the first presentation of monoclonal gammopathy of undetermined significance: a case report

Ahmad Pourmohammadi, Saba Naghavi, Iman Adibi · 2026

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Description

Ahmad Pourmohammadi, Saba Naghavi, and Iman Adibi reported a rare first sign of a blood disorder in a 2026 case paper. Monoclonal gammopathy of undetermined significance is a quiet plasma cell growth that usually causes no symptoms. It can harm nerves at the body's edges, but strikes on the central nervous system are rare.

Their patient, a healthy 54-year-old Iranian man, suffered repeated optic neuritis, flare-ups of the eye nerve. Testing traced the attacks to the gammopathy. High-dose steroids calmed the flares and rituximab kept them away. The case warns eye doctors to check blood proteins when neuritis keeps returning.

Catalog record

CREATORAhmad Pourmohammadi, Saba Naghavi, Iman Adibi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE15 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13523220

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