How Common Is Hypercortisolism in Patients With Type 2 Diabetes? Risk Factors, Epidemiology, and Making a Diagnosis Using a Dexamethasone Suppression Test
Jenine Yager Stone, Timothy S. Bailey · 2026
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Description
ImportanceHypercortisolism is an underdiagnosed contributor to metabolic dysfunction in people with Type 2 diabetes (T2D). Although overt Cushing syndrome is rare, milder forms of cortisol excess, commonly termed mild autonomous cortisol secretion (MACS), appear substantially more common in selected high‐risk populations.ObservationsChronic cortisol excess contributes directly to insulin resistance, hepatic gluconeogenesis, visceral adiposity, hypertension, dyslipidaemia and cardiovascular disease.
Catalog record
| CREATOR | Jenine Yager Stone, Timothy S. Bailey |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |