Metabolic dysfunction-associated steatotic liver disease as a systemic disorder: extrahepatic manifestations and the need for data-driven phenotyping

Sergejs Lobanovs, Maksims Jakovenko, Jeļena Ivanova, Jekaterina Nagaiceva, Jurijs Čižovs, Dmitrijs Bļizņuks · 2026

Read Metabolic dysfunction-associated steatotic liver disease as a systemic disorder: extrahepatic manifestations and the need for data-driven phenotyping by Sergejs Lobanovs, Maksims Jakovenko, Jeļena Ivanova, Jekaterina Nagaiceva, Jurijs Čižovs, Dmitrijs Bļizņuks (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13522819.txt.

Description

Sergejs Lobanovs and five colleagues argue that fatty liver disease tied to body metabolism should be seen as a whole-body disorder, in a paper dated twenty twenty-six. The disease, called MASLD, fattens the liver but also harms the heart, kidneys, brain, and pancreas. Patients differ widely in symptoms and course, so one label hides many forms. Sorting by liver traits alone misses this spread.

The authors back a data-driven way to group patients: let computer clustering find hidden subgroups from full health records, then model risks for each group. Such groups could guide who gets watched closely and which treatment fits. They note past grouping tries used unlike data, so their groups cannot be compared directly.

Catalog record

CREATORSergejs Lobanovs, Maksims Jakovenko, Jeļena Ivanova, Jekaterina Nagaiceva, Jurijs Čižovs, Dmitrijs Bļizņuks
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE61 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13522819

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