Effects of antipsychotics on brain insulin action in females: Study protocol for a placebo-controlled, crossover neuroimaging study

Nicolette Stogios, Margaret K. Hahn, Gary Remington, Ariel Graff-Guerrero, Meng-Chuan Lai, Sri Mahavir Agarwal · 2026

Read Effects of antipsychotics on brain insulin action in females: Study protocol for a placebo-controlled, crossover neuroimaging study by Nicolette Stogios, Margaret K. Hahn, Gary Remington, Ariel Graff-Guerrero, Meng-Chuan Lai, Sri Mahavir Agarwal (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13521361.txt.

Description

Stogios and five colleagues lay out a brain scan study of antipsychotic drugs and brain insulin action in women in twenty twenty-six. These drugs can trigger diabetes, and women bear the brunt. Brain insulin resistance may drive the harm, but it can not be measured straight. Nasal insulin response stands in as the probe.

Fifteen young women will cross through drug and placebo arms in both halves of the monthly cycle. Scans follow nasal insulin or placebo on set days. The team expects the insulin brain effect in the early phase only, and the drug to erase it there. No prior study has split the cycle this way.

Catalog record

CREATORNicolette Stogios, Margaret K. Hahn, Gary Remington, Ariel Graff-Guerrero, Meng-Chuan Lai, Sri Mahavir Agarwal
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13521361

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