The PHO1 protein family in phosphate export and beyond

Yves Poirier, María Victoria Aparicio Chacón · 2026

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Description

Poirier and Aparicio Chacón review the PHO1 protein family in this 2026 plant biology paper. PHO1 was first found in the plant Arabidopsis thaliana as an exporter that moves inorganic phosphate, a key nutrient, out of cells and into the root's water-carrying tissue. Related proteins appear across many living groups, in both plants and animals.

Recent cryo-electron microscopy images, which freeze proteins to reveal their shape, show these proteins act as channels with two gates controlled by inositol polyphosphate signals. The parts that bind phosphate and work the gates are nearly unchanged across species, suggesting an ancient shared job. The review also covers puzzles. The proteins sit mostly on inner cell compartments rather than the surface. The plant version also shapes responses to the stress hormone abscisic acid in seeds and leaf pores.

Catalog record

CREATORYves Poirier, María Victoria Aparicio Chacón
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE56 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13521290

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