From waste to wellness: pomelo peel derived exosome-like nanoparticles reshape gut microbiota and enhance beneficial metabolites

Liyi Li, Chaofan Chen, Tiantian Yang, Ran Tuo, Yingjie Huang, Xiaodan Zhao, Le Chu, Fatao He, Ping Li, Mingdong Lu · 2026

Read From waste to wellness: pomelo peel derived exosome-like nanoparticles reshape gut microbiota and enhance beneficial metabolites by Liyi Li, Chaofan Chen, Tiantian Yang, Ran Tuo, Yingjie Huang, Xiaodan Zhao, Le Chu, Fatao He, Ping Li, Mingdong Lu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13521061.txt.

Description

Liyi Li and nine co-authors turned pomelo peel, a fruit processing leftover, into tiny particles that feed gut microbes, in this 2026 study. The peel is rich in useful compounds but usually thrown away. The team extracted exosome-like nanoparticles, small bubbles naturally present in the peel, and tested what they do to gut bacteria.

The particles stayed stable through gut-like conditions and carried over a thousand kinds of protein. In lab fermenters seeded with human stool samples, they raised helpful bacteria such as Bifidobacterium and lowered a harmful group. They also boosted short-chain fatty acids and two plant compounds tied to health. The work frames fruit waste as a possible source of gut-friendly ingredients.

Catalog record

CREATORLiyi Li, Chaofan Chen, Tiantian Yang, Ran Tuo, Yingjie Huang, Xiaodan Zhao, Le Chu, Fatao He, Ping Li, Mingdong Lu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13521061

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