Gapless and phased genome assembly reveals post-allopolyploidization subgenomic diversification of tobacco centromeres
Weikai Chen, Shaoying Chen, Jingxuan Wang, Dian Meng, Jun Li, Li Guo · 2026
Read Gapless and phased genome assembly reveals post-allopolyploidization subgenomic diversification of tobacco centromeres by Weikai Chen, Shaoying Chen, Jingxuan Wang, Dian Meng, Jun Li, Li Guo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13520468.txt.
Description
Weikai Chen and colleagues present in 2026 a complete, gap-free genome assembly for common tobacco, a major crop formed by merging two wild species. Earlier assemblies left hundreds of gaps, especially in repetitive centre regions of chromosomes.
The new assembly spans 4.2 billion bases from end to end, with the two inherited subgenomes separated. Centre regions evolved unevenly after the merger, with frequent repositioning and distinct chemical marking patterns between subgenomes. One subgenome diverged faster in sequence. Plant scientists gain a reference for studying how merged genomes reorganise, plus a firmer base for tobacco breeding and gene work.
Catalog record
| CREATOR | Weikai Chen, Shaoying Chen, Jingxuan Wang, Dian Meng, Jun Li, Li Guo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35280 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |