Pan-cell type continuous chromatin state annotation of 1,698 epigenomes from the International Human Epigenome Consortium
Habib Daneshpajouh, Ismail Moghul, Kay C Wiese, Maxwell W Libbrecht · 2026
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Description
Habib Daneshpajouh and colleagues present in 2026 a single map of gene control states built from 1,698 human tissue samples. A global group gathered the samples over many years. Older maps were made one cell type at a time. That method grows hard to run as cell types pile up.
The team used more than 9,500 signal tracks from the samples. Their model made 33 simple scores. The scores capture start sites, boost sites, active copying and silent zones. The scores also capture cell-specific patterns. Tests of gene activity matched or beat rival methods. A side score flags zones rich in disease-linked gene changes.
Catalog record
| CREATOR | Habib Daneshpajouh, Ismail Moghul, Kay C Wiese, Maxwell W Libbrecht |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62554 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |