Point of care performance of the improved BIOCREDIT Ag Pf/Pv (pLDH/pLDH) rapid diagnostic test: a cross-sectional study at a health center setting in Ethiopia

Eshetu Molla, Eyob Fekadu, Zemed Biyazen, Fikregabrail Aberra Kassa, Melat Gebremedhin Teklewold, Tedros Nigussie, Mihret Ebabu, Mequanint Mande, Muluye Shimeles, Daniel Legese Achalu, Solomon Feleke, Mamud Umer, Derese Bekele Daba, Anneleye Fantahun, Miraf Mesfin, Adamu Bayissa, Sampa Pal, Dagmawi Hailu Yemane, Emily Gerth-Guyette, Stephan Duparc, Gonzalo J Domingo, Endalamaw Gadisa · 2026

Read Point of care performance of the improved BIOCREDIT Ag Pf/Pv (pLDH/pLDH) rapid diagnostic test: a cross-sectional study at a health center setting in Ethiopia by Eshetu Molla, Eyob Fekadu, Zemed Biyazen, Fikregabrail Aberra Kassa, Melat Gebremedhin Teklewold, Tedros Nigussie, Mihret Ebabu, Mequanint Mande, Muluye Shimeles, Daniel Legese Achalu, Solomon Feleke, Mamud Umer, Derese Bekele Daba, Anneleye Fantahun, Miraf Mesfin, Adamu Bayissa, Sampa Pal, Dagmawi Hailu Yemane, Emily Gerth-Guyette, Stephan Duparc, Gonzalo J Domingo, Endalamaw Gadisa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13520230.txt.

Description

Eshetu Molla leads a large team evaluating an improved rapid malaria test in 2026 at Ethiopian health centers. Ethiopia hosts two malaria species needing different treatment, and gene deletions forced a switch away from the older test type. Some 1,200 patients with suspected malaria at two centers gave blood for the new test, microscopy, and precise PCR as the reference.

PCR found malaria in 40.6 percent of patients. The rapid test caught 89.7 percent of PCR-confirmed infections, far above microscopy's 59.8 percent, with similar accuracy at ruling infection out. Sensitivity reached 100 percent at high parasite densities but slipped for mixed infections. Agreement with PCR was strong, supporting routine clinic use.

Catalog record

CREATOREshetu Molla, Eyob Fekadu, Zemed Biyazen, Fikregabrail Aberra Kassa, Melat Gebremedhin Teklewold, Tedros Nigussie, Mihret Ebabu, Mequanint Mande, Muluye Shimeles, Daniel Legese Achalu, Solomon Feleke, Mamud Umer, Derese Bekele Daba, Anneleye Fantahun, Miraf Mesfin, Adamu Bayissa, Sampa Pal, Dagmawi Hailu Yemane, Emily Gerth-Guyette, Stephan Duparc, Gonzalo J Domingo, Endalamaw Gadisa
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34141
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13520230

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