Current progress of labeling strategies in tissue clearing for large-scale biological visualization

Si-Wei Wang, Yu-Qian Wang, Jia-Wen Deng, Sheng-Bo Yang, Fang-Yuan Wang, Jun Wu, Jian-Guo Liu · 2026

Read Current progress of labeling strategies in tissue clearing for large-scale biological visualization by Si-Wei Wang, Yu-Qian Wang, Jia-Wen Deng, Sheng-Bo Yang, Fang-Yuan Wang, Jun Wu, Jian-Guo Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13519918.txt.

Description

Tissue clearing (TC) has transformed three-dimensional (3D) imaging by enabling deep, volumetric visualization of intact organs and complex biological systems, yet its full potential is constrained by persistent challenges in molecular labeling, including limited penetration, heterogeneous signal distribution, and compromised specificity under harsh clearing conditions.

Catalog record

CREATORSi-Wei Wang, Yu-Qian Wang, Jia-Wen Deng, Sheng-Bo Yang, Fang-Yuan Wang, Jun Wu, Jian-Guo Liu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE54 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13519918

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