Sex and Chronic Stress Alter the Distribution of Corticotropin‐Releasing Factor Receptor in Rat Hippocampus Following Oxycodone Conditioned Place Preference
Dana N. Silberstein, Zoha Baig, Batsheva Rubin, Fangmin Yu, Joshua Kogan, Jason D. Gray, Yan Zhou, Teresa A. Milner · 2026
Read Sex and Chronic Stress Alter the Distribution of Corticotropin‐Releasing Factor Receptor in Rat Hippocampus Following Oxycodone Conditioned Place Preference by Dana N. Silberstein, Zoha Baig, Batsheva Rubin, Fangmin Yu, Joshua Kogan, Jason D. Gray, Yan Zhou, Teresa A. Milner (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13519899.txt.
Description
Dana Silberstein and co-authors track how sex and long stress move a stress receptor in rat brain after a pain drug reward test, in a study from 2026. The receptor helps stress reshape the learning hub of the brain, a path tied to drug habit. Past work found sex gaps in where the receptor sits in two hub zones of calm rats.
Scope views at fine scale now add drug place tests, with and without long lock stress. Males showed more receptor on cell skins in both zones after the test than females did. Stress alone raised the gene for the receptor in males in one zone layer. Stressed females alone learned the drug place link. Shifts in receptor place in stressed females may feed that link, the authors argue.
Catalog record
| CREATOR | Dana N. Silberstein, Zoha Baig, Batsheva Rubin, Fangmin Yu, Joshua Kogan, Jason D. Gray, Yan Zhou, Teresa A. Milner |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |