A Comparative Study to Evaluate the Renoprotective Effect of Antidiabetic Drugs in Patients With Type 2 Diabetes Mellitus
Meenu Pichholiya, Raj Abhinav, Sakshi Singh, Arvind K Yadav, Sangita Gupta · 2026
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Description
Meenu Pichholiya and four colleagues compare diabetes drugs head-to-head in 2026 for kidney protection in type 2 diabetes. Diabetic kidney damage is a leading route to kidney failure worldwide, yet no earlier study had directly compared the kidney effects of common antidiabetic therapies. Their prospective study followed 100 patients at a tertiary hospital.
Blood sugar and kidney measures were tracked across follow-up visits. Metformin plus gliptin therapy significantly lowered HbA1c and blood urea. The clearest creatinine improvements appeared with metformin combined with SGLT2 inhibitors or gliptins, while insulin-only patients fared worse. Pichholiya and co-authors conclude oral combinations protect kidneys as well as sugar, while calling for larger, longer studies.
Catalog record
| CREATOR | Meenu Pichholiya, Raj Abhinav, Sakshi Singh, Arvind K Yadav, Sangita Gupta |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |