UTMD Suppresses CSF‐1 to Drive Macrophage‐Mediated Ferroptosis in Papillary Thyroid Carcinoma

Yanqiang Niu, Zhenqiang Yao, Minghua Zhang, Jiayan Zhang, Yushan Li, Jinhui Xie, Zubang Zhou · 2026

Read UTMD Suppresses CSF‐1 to Drive Macrophage‐Mediated Ferroptosis in Papillary Thyroid Carcinoma by Yanqiang Niu, Zhenqiang Yao, Minghua Zhang, Jiayan Zhang, Yushan Li, Jinhui Xie, Zubang Zhou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13519666.txt.

Description

Yanqiang Niu and co-authors present a 2026 study of a sound-based treatment for papillary thyroid carcinoma, the most common thyroid cancer. The method, called UTMD, uses ultrasound to burst tiny bubbles at the tumor. The team asked whether the method could shift the immune cells around the tumor and push cancer cells toward a type of death called ferroptosis.

They found that UTMD lowered CSF-1, a signal that turns immune cells into a tumor-helping form. With that signal cut, the helpful form fell and the attacking form rose, and cancer cells lost a shield against ferroptosis. In mice, the treatment slowed tumor growth and showed the same cell changes.

Catalog record

CREATORYanqiang Niu, Zhenqiang Yao, Minghua Zhang, Jiayan Zhang, Yushan Li, Jinhui Xie, Zubang Zhou
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE62 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13519666

Browse the full library · About the Tower of Babel