Neighborhood deprivation and oncotype DX recurrence scores among Black and White women: the interplay between race, place, and tumor biology
Jasmine M Miller-Kleinhenz, Lauren E Barber, Maret L Maliniak, Lindsay J Collin, Demetria J Smith-Graziani, Jeffery M Switchenko, Kevin C Ward, Lauren E McCullough · 2026
Read Neighborhood deprivation and oncotype DX recurrence scores among Black and White women: the interplay between race, place, and tumor biology by Jasmine M Miller-Kleinhenz, Lauren E Barber, Maret L Maliniak, Lindsay J Collin, Demetria J Smith-Graziani, Jeffery M Switchenko, Kevin C Ward, Lauren E McCullough (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13519022.txt.
Description
Jasmine M Miller-Kleinhenz and colleagues asked whether deprived neighborhoods explain why Black women face more aggressive breast tumor biology. Published in 2026, the study drew on 11,377 Black and White women in Georgia with hormone-sensitive breast cancer at early stages, diagnosed from 2010 through 2017. Each woman's neighborhood deprivation score came from census block data, and tumors were graded by the Oncotype DX recurrence score, a 21-gene test.
Living in the most deprived areas raised the odds of a high-risk tumor score only slightly overall, and not at all among Black women. Strikingly, Black women in the least deprived areas showed the highest rates of high-risk scores compared with White women nearby. The authors conclude that place alone does not explain the racial gap in tumor aggression. Readers get a careful warning against simple neighborhood stories for a complex disparity.
Catalog record
| CREATOR | Jasmine M Miller-Kleinhenz, Lauren E Barber, Maret L Maliniak, Lindsay J Collin, Demetria J Smith-Graziani, Jeffery M Switchenko, Kevin C Ward, Lauren E McCullough |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |