Intestinal fatty acid-binding protein (I-FABP) at ICU admission as early biomarker of intestinal injury and predictor of mortality in septic shock

Thorben Pape, Pedro David Wendel-Garcia, Nina Rittgerodt, Bahar Nalbant, Jan Hinrichs, Lena S. Becker, Anna M. Hunkemöller, Jakob Raith, Sören K. J. Boblitz, Jannik Ruwisch, Pia-Victoria Fangmann, Heiner Wedemeyer, Marius M. Hoeper, Christian Bode, Sascha David, Klaus Stahl, Benjamin Seeliger · 2026

Read Intestinal fatty acid-binding protein (I-FABP) at ICU admission as early biomarker of intestinal injury and predictor of mortality in septic shock by Thorben Pape, Pedro David Wendel-Garcia, Nina Rittgerodt, Bahar Nalbant, Jan Hinrichs, Lena S. Becker, Anna M. Hunkemöller, Jakob Raith, Sören K. J. Boblitz, Jannik Ruwisch, Pia-Victoria Fangmann, Heiner Wedemeyer, Marius M. Hoeper, Christian Bode, Sascha David, Klaus Stahl, Benjamin Seeliger (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13518634.txt.

Description

Thorben Pape and co-authors test a blood marker of gut injury in very ill patients in a 2026 study. In septic shock, blood flow to the gut often drops, but the harm is hard to spot early. The marker, a protein released by hurt gut cells, was measured when patients entered intensive care.

Data pooled 102 shock or lung failure patients, plus comparison groups. A cut-off level sorted patients with true gut blood loss well. Levels in the shock group ran as high as in patients with proven gut ischemia. Patients above the cut-off died within a month far more often, about 53 percent against 33 percent. The marker held its link to death after other scores were counted.

Catalog record

CREATORThorben Pape, Pedro David Wendel-Garcia, Nina Rittgerodt, Bahar Nalbant, Jan Hinrichs, Lena S. Becker, Anna M. Hunkemöller, Jakob Raith, Sören K. J. Boblitz, Jannik Ruwisch, Pia-Victoria Fangmann, Heiner Wedemeyer, Marius M. Hoeper, Christian Bode, Sascha David, Klaus Stahl, Benjamin Seeliger
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE47 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13518634

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